Research paper on gene therapy

The first speculation originated from the ancient Greek students, and some of these theories continued for many centuries. Inresearchers discovered a series of enzymes that enabled the separation of the genes in predetermined sites along the DNA molecule and their reinsertion in a reproducible manner.

These genetic advances prepared the scenario for the emergence of genetic engineering with the production of new drugs and antibodies, and as ofgene therapy has been incorporated by scientists.

The viruses are more often investigated due to their excellence of invading cells and inserting their genetic material. But these genetic instructions are merely a product of evolution, shaped so we can adapt to certain conditions which might no longer exist.

New developments in gene therapy research today

On the other hand, this allows people to possibly manipulate genes to enhance specific traits or create the perfect baby. They feel that playing God may possibly cause devastating effects to the human gene pool and may also led to misuse. E-mail: rb. Research shows that among those affected the most with the sickle cell gene are African Americans. In vivo studies in in somatic cell showed satisfactory results with approved protocols in clinical trials. But these genetic instructions are merely a product of evolution, shaped so we can adapt to certain conditions which might no longer exist. Further on, diffrent strategies are described, which are often used for this purpose. Genetic-scientific studies initiated in the early s, when the Austrian monk, Gregor Mendel, in a series of experiments with green peas, described the inheritance pattern by observing the traces that were inherited as separate units, which we know today as genes. This paper will demonstrate how Gene Therapy is an important step in revolutionizing medicine and treating disease. Although gene testing had been around and used for various procedures and breakthroughs, gene therapy had the potential to change the face of research, as we knew it. Thus, the mutated erythrocytes result in an inadequate supply of oxygen being transported throughout the body. Up until , little was known as to the physical nature of genes, which was when the American biochemist, James Watson, and the British biophysicist, Francis Crick, developed the revolutionary model of the double strand DNA. These genetic advances prepared the scenario for the emergence of genetic engineering with the production of new drugs and antibodies, and as of , gene therapy has been incorporated by scientists. Knowing which gene controls what trait and causes what genetic disease will arm doctors with a powerful tool to treat their patients at the molecular level.

E-mail: rb. This number is set to see an increase over the years if adequate care in research is not given.

Further on, diffrent strategies are described, which are often used for this purpose. Gene therapy The ability to make local modificiations in the human genome has been the objective of Medicine since the knowledge of DNA as the basic unit of heredity.

gene therapy research paper pdf

This article is helpful at explaining the way DNA is inherited and how we can trace our genes back to our ancestors. Inaboutpeople died from the disease as aboutcases of ailing lung cancer patients were diagnosed that year.

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Gene Therapy Literature and Research Journals